Issue 18, 2025

Exploring the homing effect and enhanced drug delivery potential of small extracellular vesicles

Abstract

We propose a strategy of assembling small extracellular vesicles (sEVs) and liposomes into dimers to explore the homing effect and the drug delivery potential of sEVs. The uptake rate of dimers by parental cells is 2.6–4.9 times higher than that by other cells, showing enhanced drug delivery capacity.

Graphical abstract: Exploring the homing effect and enhanced drug delivery potential of small extracellular vesicles

Supplementary files

Article information

Article type
Communication
Submitted
24 Nov 2024
Accepted
01 Feb 2025
First published
10 Feb 2025

Chem. Commun., 2025,61, 3708-3711

Exploring the homing effect and enhanced drug delivery potential of small extracellular vesicles

Q. Zhang, K. Cao, T. Ren, H. Wu and Z. Xu, Chem. Commun., 2025, 61, 3708 DOI: 10.1039/D4CC06241H

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