Issue 26, 2025

ESIPT-driven imaging: a thiazole probe for lipid droplets and plasma membranes

Abstract

Fluorescence imaging allows high-resolution visualization of cellular processes. This study introduces a novel ESIPT probe with dual localization for lipid droplets and plasma membranes. Initially, the blue channel imaging reveals the probe's affinity for the plasma membrane, and then it redistributes into lipid droplets, showcasing its strong affinity for the hydrophobic lipid core.

Graphical abstract: ESIPT-driven imaging: a thiazole probe for lipid droplets and plasma membranes

Supplementary files

Article information

Article type
Communication
Submitted
13 Nov 2024
Accepted
03 Mar 2025
First published
03 Mar 2025

Chem. Commun., 2025,61, 5023-5026

ESIPT-driven imaging: a thiazole probe for lipid droplets and plasma membranes

J. L. Belmonte-Vázquez, J. L. Cortes-Muñoz, A. Romo-Pérez, B. Rodríguez-Molina and A. Jiménez-Sánchez, Chem. Commun., 2025, 61, 5023 DOI: 10.1039/D4CC06049K

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