Supramolecular-platform-assisted selective recognition of uric acid with high sensitivity via microenvironment modulation of a self-assembled probe

Abstract

This report demonstrates a unique route for translating a non-responsive fluorophore into a responsive one to optically recognize uric acid (UA) in physiological-mimicking conditions. The explicit ‘turn ON–turn OFF’ fluorescence switching upon sequential disaggregation–reaggregation of the self-aggregated 3,3′-bisindolyl(phenyl)methane molecules materializes a straightforward, trouble-free supramolecular UA sensing platform.