Cesar A. D. Zaragoza, Gabriel S. G. Peagno, Ana J. A. Minguine and Airton G. Salles, Jr
Org. Biomol. Chem., 2024,22, 2359-2364
DOI:
10.1039/D4OB00218K,
Communication
We present a metal-free method to synthesize secondary and tertiary propargylamines from primary and secondary amines and alkynes using light-mediated persulfate activation and phase-transfer catalysis. Our method explores a tandem oxidative coupling/alkynylation reaction for the generation of diverse compounds, highlighting the sustainability of the process and its wide scope.