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We present a metal-free method to synthesize secondary and tertiary propargylamines from primary and secondary amines and alkynes using light-mediated persulfate activation and phase-transfer catalysis. Our method explores a tandem oxidative coupling/alkynylation reaction for the generation of diverse compounds, highlighting the sustainability of the process and its wide scope.

Graphical abstract: Metal-free synthesis of propargylamines via light-mediated persulfate activation and phase-transfer catalysis

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