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Correction: Nucleic acid detection with single-base specificity integrating isothermal amplification and light-up aptamer probes

Jaekyun Baek ac, Jihyun Park b and Youngeun Kim *abc
aInterdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea. E-mail: youngeunkim@snu.ac.kr
bDepartment of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea
cResearch Institute of Advanced Materials, Seoul National University, Seoul, 08826, Republic of Korea

Received 24th October 2024 , Accepted 24th October 2024

First published on 30th October 2024


Abstract

Correction for ‘Nucleic acid detection with single-base specificity integrating isothermal amplification and light-up aptamer probes’ by Jaekyun Baek et al., Nanoscale, 2024, https://doi.org/10.1039/D4NR01638F.


The original article contains an incorrect version of Fig. 1. The correct version of Fig. 1 is shown below.
image file: d4nr90197e-f1.tif
Fig. 1 Schematic representation of CLASSIC. CLASSIC consists of three distinct reactions: amplification, digestion, and detection. Target DNA is exponentially amplified through recombinase polymerase amplification. Effectively, only the target DNA strand synthesized from the forward primer (green) that has pt modifications (black hexagon) remains intact after the enzymatic digestion. As a result, a pair of SDA probes (UHP and DHP) hybridizes to the single-stranded target and forms an aptameric core, leading to a dramatic enhancement in AO fluorescence.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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