Correction: Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms

Abstract

Correction for ‘Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms’ by Lydia W. Njenga et al., Dalton Trans., 2023, 52, 5823–5847, https://doi.org/10.1039/D3DT00366C.

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The authors regret that on page 5824 the structures of compounds 2, 3 and 4 were incorrect, showing protonated ligands. The corrected structures are shown below.

Fig. 7 also showed incorrect chemical structures; the corrected figure is shown below.

Fig. 7 Copper(DTC)₂ from the reduction disulfiram by Cys-SH which releases DTC.

Fig. 8 also showed incorrect chemical structures; the correct figure is shown below.

Fig. 8 Release of DTC by GGT leading to binding to copper in vivo.

On page 5825, the statement “Disulfiram (…) and clioquinol release copper in a reductive intracellular environment and have been shown to have anticancer effects in several clinical trials using mouse models.” was supported by incorrect references, and this statement should be supported by references 67, 68, and 16 of the original article.

On page 5831, the statement “The strong trans-influence of the sulphur atoms…” should be rephrased to refer to “the relatively strong trans-influence of the groups coordinated through sulphur atoms…”.

The authors regret that a large number of references used incorrect page numbers. These references are shown in their correct form here, with the following citation numbers:

Reference here	Reference in original article	Reference here	Reference in original article
1	11	21	136
2	21	22	143
3	27	23	144
4	39	24	165
5	52	25	172
6	66	26	177
7	67	27	181
8	68	28	191
9	71	29	196
10	73	30	202
11	74	31	203
12	76	32	228
13	81	33	259
14	83	34	260
15	85	35	262
16	97	36	275
17	107	37	276
18	114	38	282
19	115
20	133

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.

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