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Correction: 6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype
Jingjing
Yao
a,
Zhenhua
Du
a,
Zibo
Li
a,
Shuhui
Zhang
a,
Yukun
Lin
a,
Haiyun
Li
a,
Lin
Zhou
a,
Yuehua
Wang
a,
Guixi
Yan
a,
Xianchuang
Wu
*d,
Yongjian
Duan
c and
Gangjun
Du
*abc
aInstitute of Pharmacy, Pharmacy College of Henan University, Jinming District, Kaifeng, Henan Province 475004, China. E-mail: 10200029@vip.henu.edu.cn; Fax: +86-0371-23880680; Tel: +86-0371-23880680
bSchool of Pharmacy and Chemical Engineering, Zhengzhou University of Industry Technology, Xinzheng, Henan Province 451150, China
cDepartment of Oncology, The first hospital Affiliated to Henan University, Kaifeng, Henan Province 475001, China
dDepartment of Pharmacy, Huaihe Hospital Affiliated to Henan University, Kaifeng, Henan Province 475001, China. E-mail: wuxc128@163.com
First published on 14th July 2023
Abstract
Correction for ‘6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype’ by Jingjing Yao et al., Food Funct., 2018, 9, 4611–4620, https://doi.org/10.1039/C8FO01147H.
The authors regret that there were errors in Fig. 2A and 3A. Some duplicated panels appeared in Fig. 2A (F4/80 and iNOS+ macrophages of LEC group) and Fig. 3A (iNOS+ M2 macrophages of nor-NOHA group and 20 μg mL−1 6G + Pexidartinib group). The corrected Fig. 2 and 3 are shown below.
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| Fig. 2 6-Gingerol changed macrophage polarization in lung tissues. (A) Lung interstitial macrophage phenotypes indicated by immunofluorescence. (B) The fluorescence intensity of different macrophage phenotypes. (C) Cytokines in alveolar cavity examined by ELISA. The data present Mean ± SD (n = 5), the experiments were repeated 2 times, and statistical significance was determined by a t test. *P < 0.05, **P < 0.01 vs. Control; #P < 0.05, ##P < 0.01 vs. Normal. | ||
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| Fig. 3 6-Gingerol changed macrophage polarization in vitro. (A) The effect of 6-gingerol on iNOS and arginase in LPS-induced M1 and IL-4-induced M2 macrophages indicated by immunofluorescence. (B) The fluorescence intensity of iNOS and arginase in LPS-induced M1 macrophages. (C) The fluorescence intensity of iNOS and arginase in IL-4-induced M2 macrophages. The data present Mean ± SD (n = 5); the experiments were repeated 3 times, and statistical significance was determined by a t test. *P < 0.05, **P < 0.01 vs. Control. | ||
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