Issue 14, 2023

Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

Abstract

Transferrin (Tf) has been effectively used to promote the cellular uptake of HAIYPRH (T7) peptide-conjugated nano-drugs. In this study, the enhancing effect of Tf on T7-decorated nano-drug transport was investigated using force tracing and nano-indentation techniques at a single-particle/cell level. Furthermore, the results were confirmed by ensemble fluorescence imaging.

Graphical abstract: Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

Supplementary files

Article information

Article type
Communication
Submitted
21 Jan 2023
Accepted
09 Mar 2023
First published
09 Mar 2023

Phys. Chem. Chem. Phys., 2023,25, 9766-9771

Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs

X. Zhang, M. Shan, S. Li, J. Zhao, X. Pang, G. Yang and Y. Shan, Phys. Chem. Chem. Phys., 2023, 25, 9766 DOI: 10.1039/D3CP00342F

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