Early detection of lung cancer biomarkers in exhaled breath by modified armchair stanene nanoribbons

Abstract

In this study, we analyze armchair stanene nanoribbons as excellent sensing substances for the early diagnosis of lung cancer using density functional theory and the non-equilibrium Green function. Four modified configurations of surface- and edge-defected armchair stanene nanoribbons were studied to improve the sensing performance. Our probes indicated that the adsorption energy of armchair stanene nanoribbons is at least five times greater than that of other previously reported substances, such as single-wall carbon nanotubes, phosphorene, and silicene. A noticeable reduction in the current was observed, implying the high sensitivity of our sensing configurations. The adsorption energy and current results suggest that configurations with a single vacancy and edge defects improve the sensitivity and selectivity of the system because of their free dangling bonds. The calculated results demonstrate that the both-side edge defected armchair stanene nanoribbons reduce the adsorption energy to −8.35 eV and increase the sensitivity up to 45% for toluene detection. This reduction in adsorption energy and the surge of sensitivity shows ultra-high sensing performance, yielding a more efficient structure for the future design of early-diagnosis lung cancer sensing applications, thus improving lung cancer patients’ survival and life expectancy.