Issue 9, 2022

Self-assembly of amphiphilic amino acid derivatives for biomedical applications

Abstract

Amino acids are one of the simplest biomolecules and they play an essential role in many biological processes. They have been extensively used as building blocks for the synthesis of functional nanomaterials, thanks to their self-assembly capacity. In particular, amphiphilic amino acid derivatives can be designed to enrich the diversity of amino acid-based building blocks, endowing them with specific properties and/or promoting self-assembly through hydrophobic interactions, hydrogen bonding, and/or π-stacking. In this review, we focus on the design of various amphiphilic amino acid derivatives able to self-assemble into different types of nanostructures that were exploited for biomedical applications, thanks to their excellent biocompatibility and biodegradability.

Graphical abstract: Self-assembly of amphiphilic amino acid derivatives for biomedical applications

Article information

Article type
Review Article
Submitted
08 Dec 2021
First published
12 Apr 2022

Chem. Soc. Rev., 2022,51, 3535-3560

Self-assembly of amphiphilic amino acid derivatives for biomedical applications

T. Wang, C. Ménard-Moyon and A. Bianco, Chem. Soc. Rev., 2022, 51, 3535 DOI: 10.1039/D1CS01064F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements