Nondirected Pd-catalyzed aerobic C–H alkenylation of ruthenocene and ferrocene

Abstract

Pd-catalyzed alkenylations of metallocenes via C–H activation were developed using electronically tunable pyrazolonaphthyridine (PzNPy) ligands. Ferrocene was alkenylated using the most electron-deficient ligand in the series, whereas the less reactive ruthenocene needed balancing of the electrophilicity and stability of catalysts. Various alkenes were installed, allowing fine-tuning of redox potentials.