Issue 73, 2022
From the journal:

Chemical Communications

Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA†

Anand Lopeza  and  Juewen Liu ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, ON, Canada
E-mail: liujw@uwaterloo.ca

Abstract

K+ enhanced the intrinsic fluorescence of a series of G-quadruplex DNAs, while Pb2+ quenched the fluorescence. The metals showed interesting quadruplex binding kinetics with various DNA sequences.

Graphical abstract: Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA

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Article information

DOI
https://doi.org/10.1039/D2CC03967B
Article type
Communication
Submitted
15 Jul 2022
Accepted
19 Aug 2022
First published
19 Aug 2022

Chem. Commun., 2022,58, 10225-10228

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Probing metal-dependent G-quadruplexes using the intrinsic fluorescence of DNA

A. Lopez and J. Liu, Chem. Commun., 2022, 58, 10225 DOI: 10.1039/D2CC03967B

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