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Abstract | Cited by

A sustainable strategy for the alkylation of heterocycles is presented. The protocol relies on the in situ generation and further in-line use of alkyl zinc sulfinates through a continuous-flow system. The environmentally friendly character of the protocol is assured by the use of a green solvent mixture, the presence of a metal free oxidant and low waste generation.

Graphical abstract: Continuous-flow synthesis of alkyl zinc sulfinates for the direct photofunctionalization of heterocycles

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