Issue 12, 2021

Cyanation: a photochemical approach and applications in organic synthesis

Abstract

Photoredox chemistry has emerged as an efficient tool in catalyzing organic reactions as it utilizes light as an energy source without any external initiator or reagent. The cyanide group is one of the most crucial organic scaffolds as it is present in various bioactive and pharmaceutical drugs and has the ability to be converted to other multiple functional groups. In the last few years, a great advancement has been achieved in photocatalytic cyanation strategies in terms of homogeneous and heterogeneous photocatalysis. This review summarizes various photochemical strategies in C–CN, X–CN (X = N, S), and non-cyanide R–CN bond formation.

Graphical abstract: Cyanation: a photochemical approach and applications in organic synthesis

Article information

Article type
Review Article
Submitted
29 Jan 2021
Accepted
27 Mar 2021
First published
31 Mar 2021

Org. Chem. Front., 2021,8, 3166-3200

Cyanation: a photochemical approach and applications in organic synthesis

R. I. Patel, S. Sharma and A. Sharma, Org. Chem. Front., 2021, 8, 3166 DOI: 10.1039/D1QO00162K

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