Open Access Article
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Retraction: Convenient synthesis of pyrimidine 2′-deoxyribonucleoside monophosphates with important epigenetic marks at the 5-position
Song
Zheng
a,
Ai
Tran
a,
Alyson M.
Curry
b,
Dawanna S.
White
b and
Yana
Cen
*bc
aDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT 05446, USA
bDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA 23219, USA. E-mail: ceny2@vcu.edu; Tel: +1 804-828-7405
cInstitute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, USA
First published on 25th February 2021
Abstract
Retraction of ‘Convenient synthesis of pyrimidine 2′-deoxyribonucleoside monophosphates with important epigenetic marks at the 5-position’ by Song Zheng et al., Org. Biomol. Chem., 2020, 18, 5164–5173, DOI: 10.1039/D0OB00884B.
The Royal Society of Chemistry hereby wholly retracts this Organic & Biomolecular Chemistry article due to concerns about the reproducibility of the data.
The Royal Society of Chemistry has been contacted by the authors of this article to alert us that recent experiments by their group have shown that some results are not reproducible, especially the yields of several key intermediates. Given the focus on the easy access to epigenetically important nucleoside monophosphates, unreliable yields significantly impact confidence in the results. Ahead of a thorough re-examination of the entire study, in order to preserve the rigor of the scientific record, the signing authors have chosen to retract the article and they would like to apologise for any inconvenience this may have caused for readers.
Signed: Song Zhenga, Ai Trana, Alyson M. Curryb, Dawanna S. Whiteb and Yana Cen*b,c, 9th February 2021.
Retraction endorsed by Katie Lim, Executive Editor, Organic & Biomolecular Chemistry.
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