Access to diverse organosulfur compounds via arynes: a comprehensive review on Kobayashi's aryne precursor

Abstract

Arynes are highly reactive transient intermediates having enormous applications in organic synthesis. In the last three decades aryne chemistry has shown incredible developments in carbon–carbon and carbon–heteroatom bond formation reactions. After the discovery of Kobayashi's protocol for the generation of aryne intermediates in a mild way, this field of chemistry witnessed rapid growth in synthetic organic chemistry. One aspect of development in this field involves C–S bond formation under mild conditions which has a tremendous scope for the synthesis of various important organosulfur building blocks.