Issue 3, 2021
From the journal:

RSC Medicinal Chemistry

Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice†

Baris A. Borsa,*a   Mert Sudagidan,b   Mehmet E. Aldag,c   Isik I. Baris,d   Elif E. Acar,b   Cagatay Acuner,e   Murat Kavrukf  and  Veli C. Ozalp ORCID logo *g  

* Corresponding authors

a Nucleic Acid Technologies Lab, Department of Physics, Chemistry and Biology (IFM), Linköping University, Linköping, Sweden
E-mail: Baris.ata.borsa@liu.se

b Kit-Argem Research Centre, Konya Food and Agriculture University, Meram, Konya, Turkey

c Department of Medical Microbiology, Corlu State Hospital, Tekirdag, Turkey

d Department of Pathology, Cakmak Erdem Hospital, Istanbul, Turkey

e Department of Medical Microbiology, Medical School, Yeditepe University, Istanbul, Turkey

f Test and Calibration Center, Turkish Standards Institution (TSE), 41400, Gebze, Kocaeli, Turkey

g Department of Medical Biology, Medical School, Atilim University, Incek, Ankara, Turkey
E-mail: Cengiz.ozalp@atilim.edu.tr

Abstract

Antibiotic therapy comes with disturbances on human microbiota, resulting in changes of bacterial communities and thus leading to well-established health problems. In this study, we demonstrated that targeted teicoplanin administration maintains the faecal microbiota composition undisturbed in a mouse model while reaching therapeutic improvements for S. aureus infection.

Graphical abstract: Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D0MD00347F
Article type
Research Article
Submitted
09 Oct 2020
Accepted
13 Dec 2020
First published
15 Jan 2021

RSC Med. Chem., 2021,12, 380-383

Permissions

Request permissions

Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

B. A. Borsa, M. Sudagidan, M. E. Aldag, I. I. Baris, E. E. Acar, C. Acuner, M. Kavruk and V. C. Ozalp, RSC Med. Chem., 2021, 12, 380 DOI: 10.1039/D0MD00347F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements