Expression of concern: Enzyme-mediated dual-targeted-assembly realizes a synergistic anticancer effect

Abstract

Expression of concern for ‘Enzyme-mediated dual-targeted-assembly realizes a synergistic anticancer effect’ by Dingze Mang et al., Chem. Commun., 2019, 55, 6126–6129, DOI: 10.1039/C9CC02715G.

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The Royal Society of Chemistry has been notified about the outcome of an investigation at the Okinawa Institute of Science and Technology that the results presented in this Chemical Communications article may not be reliable according to the following report: https://groups.oist.jp/system/files/2021-01-27_research-misconduct_en.pdf. The authors dispute the contents of the report and have provided the following statement:

We disagree with the OIST report and have addressed all scientific points raised in our official statement published on Retraction Watch: https://retractionwatch.com/2021/02/03/okinawa-researcher-suspended-for-faking-data-denies-committing-misconduct/#more-121443. We also provided the spectra of the target molecules reported in the article to Retraction Watch which are free to download: https://retractionwatch.com/wp-content/uploads/2021/02/Compound-1-and-2.pdf.

The co-authors are repeating the experiments as part of an ongoing expanded study that follows up on this Chemical Communications article.

Chemical Communications is publishing this Expression of Concern to alert readers that we are presently unable to confirm the accuracy of the data reported in this paper. An expression of concern will continue to be associated with the article until we receive conclusive evidence regarding the reliability of the reported data.

 

Richard Kelly

16th June 2021

Executive Editor, Chemical Communications

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