Hierarchical protein self-assembly into dynamically controlled 2D nanoarrays via host–guest chemistry

Yijia Li; Linlu Zhao; Hongwei Chen; Ruizhen Tian; Fei Li; Quan Luo; Jiayun Xu; Chunxi Hou; Junqiu Liu

doi:10.1039/D1CC03654H

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Hierarchical protein self-assembly into dynamically controlled 2D nanoarrays via host–guest chemistry†

Yijia Li,‡^a Linlu Zhao,‡^b Hongwei Chen,^b Ruizhen Tian,^a Fei Li,^a Quan Luo,

^a Jiayun Xu,^ac Chunxi Hou*^a and Junqiu Liu

*^ac

Author affiliations

* Corresponding authors

^a State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Road, Changchun 130012, China
E-mail: chunxihou@jlu.edu.cn, junqiuliu@jlu.edu.cn

^b The First Affiliated Hospital of Hainan Medical University, Hainan Medical University, Haikou 571199, China

^c College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 311121, China

Abstract

A dynamically reversible two-dimensional (2D) protein assembly system was designed based on host–guest interactions and was triggered to disassemble via a competition mechanism. The artificially tunable and reversible protein assembly architectures hold great potential for on/off switches in bio-systems.

This article is part of the themed collection: Host-Guest Chemistry

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Article information

DOI: https://doi.org/10.1039/D1CC03654H
Article type: Communication
Submitted: 07 Jul 2021
Accepted: 15 Sep 2021
First published: 15 Sep 2021

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Chem. Commun., 2021,57, 10620-10623

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Hierarchical protein self-assembly into dynamically controlled 2D nanoarrays via host–guest chemistry

Y. Li, L. Zhao, H. Chen, R. Tian, F. Li, Q. Luo, J. Xu, C. Hou and J. Liu, Chem. Commun., 2021, 57, 10620 DOI: 10.1039/D1CC03654H

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Chemical Communications

Hierarchical protein self-assembly into dynamically controlled 2D nanoarrays via host–guest chemistry†

Abstract

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Hierarchical protein self-assembly into dynamically controlled 2D nanoarrays via host–guest chemistry

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