Issue 50, 2021
From the journal:

Chemical Communications

Selenium-engineered covalent organic frameworks for high-efficiency and long-acting cancer therapy†

Xiuyan Wan,‡a   Tong Wu,‡a   Liqun Song,a   Wei Pan, ORCID logo a   Na Li ORCID logo *a  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China
E-mail: lina@sdnu.edu.cn, tangb@sdnu.edu.cn

Abstract

A porphyrin-containing covalent organic framework (COF) was synthesized as a substrate for decorating selenium nanoparticles (Se NPs) via in situ reduction. Se NP-mediated therapy (SeT) was carried out in conjunction with photodynamic therapy (PDT) to provide an increased anticancer effect and remedy the constrained efficacy of PDT.

Graphical abstract: Selenium-engineered covalent organic frameworks for high-efficiency and long-acting cancer therapy

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Article information

DOI
https://doi.org/10.1039/D1CC01830B
Article type
Communication
Submitted
06 Apr 2021
Accepted
18 May 2021
First published
18 May 2021

Chem. Commun., 2021,57, 6145-6148

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Selenium-engineered covalent organic frameworks for high-efficiency and long-acting cancer therapy

X. Wan, T. Wu, L. Song, W. Pan, N. Li and B. Tang, Chem. Commun., 2021, 57, 6145 DOI: 10.1039/D1CC01830B

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