An ultrasensitive chemiluminescence strategy based on a microchip platform for telomerase detection at a single-cell level

Abstract

An ultrasensitive chemiluminescence strategy based on signal amplification with a microchip platform was proposed to detect telomerase. This strategy was successfully applied to the determination of lysate samples from HL-7702, HeLa, A549 and MCF-7 cell lines with the detection limit lower than 1 HeLa cell.