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Correction: In vitro vascularization of tissue engineered constructs by non-viral delivery of pro-angiogenic genes

Helena R. Moreira ab, Rosanne M. Raftery cde, Lucília P. da Silva ab, Mariana T. Cerqueira ab, Rui L. Reis ab, Alexandra P. Marques ab and Fergal J. O'Brien *cde
a3B's Research Group, I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Avepark, Barco, 4805-017 Guimarães, Portugal
bICVS/3B's – PT Government Associate Laboratory, Braga/Guimarães 4805-017, Portugal
cTissue Engineering Research Group, Dept. of Anatomy & Regenerative Medicine, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland. E-mail: fjobrien@rcsi.ie
dTrinity Centre for Biomedical Engineering, Trinity College Dublin (TCD), Dublin, Ireland
eAdvanced Materials and Bioengineering Research (AMBER) Centre, RCSI & TCD, Dublin, Ireland

Received 22nd January 2021 , Accepted 22nd January 2021

First published on 29th January 2021


Abstract

Correction for ‘In vitro vascularization of tissue engineered constructs by non-viral delivery of pro-angiogenic genes’ by Helena R. Moreira et al., Biomater. Sci., 2021, DOI: 10.1039/d0bm01560a.


The authors regret the incorrect version of Fig. 3 was included in the original manuscript. The correct version of Fig. 3 is as shown below:
image file: d1bm90010b-f3.tif
Fig. 3 hDMECs organization on COL-GAG and GG-HyA scaffolds after 3 and 7 days. (A) Chosen plasmids were delivered to hDFbs and seeded in different scaffolds. The angiogenic capacity of the system is maximized through the release of angiogenic proteins providing a 3D microenvironment for endothelial cells proliferation and organization. (B) hDFbs were transfected with PEI-pVEGF, Ch-pFGF2 and the dual combination of both (P + C) and seeded on COL-HyA, COL-ChS and GG-HyA scaffolds with hDMECs. Control corresponds to co-cultures where hDFbs were not transfected. In all scaffolds, co-culture of hDMECs (CD31) with PEI-pVEGF hDFbs showed the formation of an extensive CD31 + endothelial network (white arrows) in all conditions after 7 days. Scale bar: 75 μm.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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