Xinchi Gong, Chunyin Zhu and Long-Wu Ye
Org. Biomol. Chem., 2020,18, 1843-1850
DOI:
10.1039/C9OB02754H,
Review Article
This article gives a short review on the visible-light promoted synthesis of α-functionalized ketones from alkenes. Various α-functionalized ketones, including α-halo, sulfinyl/sulfonyl, aryl, azido and thiocyanato ketones can be synthesized from the reaction of alkenes with different radical species generated by visible-light catalysis. These transformations typically use dioxygen as the terminal oxidant and do not require a transition metal to activate the double bond, which is quite different from the transition-metal catalysed reactions (Wacker oxidation or hydroformylation).