Issue 5, 2020
From the journal:

New Journal of Chemistry

A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA†

Ding Ma,a   Sheng-Run Zheng, ORCID logo *a   Jun Fan, ORCID logo a   Song-Liang Cai, ORCID logo a   Zong Dai, ORCID logo b   Xiao-Yong Zou, ORCID logo b   Shao-Hua Tengc  and  Wei-Guang Zhang*a  

* Corresponding authors

a School of Chemistry, South China Normal University, Guangzhou, China
E-mail: zhengsr-scnu.edu.cn, wgzhang-scnu.edu.cn
Fax: +86-20-39310210

b School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China

c School of Computer Science and Technology, Guangdong University of Technology, Guangzhou 510006, China

Abstract

A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in miRNA detection.

Graphical abstract: A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA

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Article information

DOI
https://doi.org/10.1039/C9NJ04600C
Article type
Letter
Submitted
06 Sep 2019
Accepted
19 Dec 2019
First published
20 Dec 2019

New J. Chem., 2020,44, 1684-1688

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A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA

D. Ma, S. Zheng, J. Fan, S. Cai, Z. Dai, X. Zou, S. Teng and W. Zhang, New J. Chem., 2020, 44, 1684 DOI: 10.1039/C9NJ04600C

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