Issue 38, 2020

Observation of the changes in the chemical composition of lipid droplets using Raman microscopy

Abstract

We report the dynamics of lipid droplet formation induced by introducing cis- and/or trans-fatty acids into cells. Raman imaging allows the chemical analysis of each droplet, showing that exogenous fatty acids initially enter original endogenous droplets, then induce additional droplets containing endogenous lipids, and finally form their droplets.

Graphical abstract: Observation of the changes in the chemical composition of lipid droplets using Raman microscopy

Supplementary files

Article information

Article type
Communication
Submitted
17 Jul 2020
Accepted
07 Sep 2020
First published
08 Sep 2020

Phys. Chem. Chem. Phys., 2020,22, 21646-21650

Observation of the changes in the chemical composition of lipid droplets using Raman microscopy

H. Takahashi, A. Yanamisawa, S. Kajimoto and T. Nakabayashi, Phys. Chem. Chem. Phys., 2020, 22, 21646 DOI: 10.1039/D0CP03805A

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