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Correction: Dopamine-melanin nanoparticles scavenge reactive oxygen and nitrogen species and activate autophagy for osteoarthritis therapy
Gang
Zhong
a,
Xueyuan
Yang
b,
Xianfang
Jiang
c,
Anil
Kumar
b,
Huiping
Long
d,
Jin
Xie
*b,
Li
Zheng
*a and
Jinmin
Zhao
a
aGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Department of Orthopaedics Trauma and Hand Surgery, Guangxi Medical University, Nanning, 530021, China. E-mail: zhengli224@163.com
bDepartment of Chemistry, University of Georgia, Athens, Georgia 30602, USA. E-mail: jinxie@uga.edu
cThe College of Stomatology, Guangxi Medical University, Nanning, 530021, China
dDepartment of Neurology, Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China
First published on 4th December 2019
Abstract
Correction for ‘Dopamine-melanin nanoparticles scavenge reactive oxygen and nitrogen species and activate autophagy for osteoarthritis therapy’ by Gang Zhong et al., Nanoscale, 2019, 11, 11605–11616.
The authors have noticed that there were a number of errors in Fig. 3c in the original article. These errors were associated with data normalization. A corrected version of Fig. 3 is provided below.
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| Fig. 3 Chondro-protective effects of DM nanoparticles on IL-1β-induced chondrocytes. (a) MTT assay was to detect the cytotoxicity of DM nanoparticles (control: only with 10 ng mL−1 IL-1β). (b–e) Chondrocytes were treated with IL-1β (10 ng mL−1) and/or various concentrations of DM nanoparticles (10, 30, 60 μg mL−1) for 24 hours. (b) FDA//PI stained for cell viability. (c) Flow cytometry for cell apoptosis. (d) Quantitative flow cytometry for apoptosis. (e) Quantification of matrix production of GAG (n = 6) for cell proliferation. Normal (without IL-1β); IL-1β (with 10 ng mL−1 IL-1β); IL-1β + DM 10 (with 10 ng mL−1 IL-1β and 10 μg ml−1 DM nanoparticles); IL-1β + DM 30 (with 10 ng mL−1 IL-1β and 30 μg ml−1 DM nanoparticles); IL-1β + DM 60 (with 10 ng mL−1 IL-1β and 60 μg ml−1 DM nanoparticles). Values are presented as means ± SD, n = 6. *, P < 0.05; **, P < 0.01; ***, P < 0.001, relative to the normal group; #, P < 0.05; ##, P < 0.01; ###, P < 0.001, relative to the IL-1β group. Scale bar, 40 μm. | ||
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