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Correction: Dopamine-melanin nanoparticles scavenge reactive oxygen and nitrogen species and activate autophagy for osteoarthritis therapy

Gang Zhonga, Xueyuan Yangb, Xianfang Jiangc, Anil Kumarb, Huiping Longd, Jin Xie*b, Li Zheng*a and Jinmin Zhaoa
aGuangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, Department of Orthopaedics Trauma and Hand Surgery, Guangxi Medical University, Nanning, 530021, China. E-mail: zhengli224@163.com
bDepartment of Chemistry, University of Georgia, Athens, Georgia 30602, USA. E-mail: jinxie@uga.edu
cThe College of Stomatology, Guangxi Medical University, Nanning, 530021, China
dDepartment of Neurology, Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China

Received 26th November 2019 , Accepted 26th November 2019

First published on 4th December 2019


Correction for ‘Dopamine-melanin nanoparticles scavenge reactive oxygen and nitrogen species and activate autophagy for osteoarthritis therapy’ by Gang Zhong et al., Nanoscale, 2019, 11, 11605–11616.


The authors have noticed that there were a number of errors in Fig. 3c in the original article. These errors were associated with data normalization. A corrected version of Fig. 3 is provided below.
image file: c9nr90272d-f1.tif
Fig. 3 Chondro-protective effects of DM nanoparticles on IL-1β-induced chondrocytes. (a) MTT assay was to detect the cytotoxicity of DM nanoparticles (control: only with 10 ng mL−1 IL-1β). (b–e) Chondrocytes were treated with IL-1β (10 ng mL−1) and/or various concentrations of DM nanoparticles (10, 30, 60 μg mL−1) for 24 hours. (b) FDA//PI stained for cell viability. (c) Flow cytometry for cell apoptosis. (d) Quantitative flow cytometry for apoptosis. (e) Quantification of matrix production of GAG (n = 6) for cell proliferation. Normal (without IL-1β); IL-1β (with 10 ng mL−1 IL-1β); IL-1β + DM 10 (with 10 ng mL−1 IL-1β and 10 μg ml−1 DM nanoparticles); IL-1β + DM 30 (with 10 ng mL−1 IL-1β and 30 μg ml−1 DM nanoparticles); IL-1β + DM 60 (with 10 ng mL−1 IL-1β and 60 μg ml−1 DM nanoparticles). Values are presented as means ± SD, n = 6. *, P < 0.05; **, P < 0.01; ***, P < 0.001, relative to the normal group; #, P < 0.05; ##, P < 0.01; ###, P < 0.001, relative to the IL-1β group. Scale bar, 40 μm.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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