Issue 28, 2019

Tracking pereirine and flavopereirine in pau-pereira using Raman and SERS spectroscopies

Abstract

Pau-pereira (Geissospermum vellosii) is a native tree of Brazil from which a mixture of alkaloids named pereirine and the compound flavopereirine has been isolated. Preventive and curative properties have been recorded by ethnopharmacological studies performed with Geissospermum species. Pereirine has been prescribed as a herbal drug since the early 1830's and flavopereirine has shown anticancer properties. In this work, the alkaloid content produced by G. vellosii has been investigated from 20 commercial samples collected from different localities. The identification of compounds has been performed by Raman and surface-enhanced Raman scattering (SERS) spectroscopies, with the assignment of Raman bands supported by theoretical calculations. The obtained results have demonstrated that Raman and SERS techniques are suitable to detect both pereirine and flavopereirine from raw materials, infusions prepared as teas and ethanolic extracts, which is the extraction procedure to prepare tinctures. Chemometric analysis was able to discriminate the alkaloid content present in each sample type according to the extraction methodology.

Graphical abstract: Tracking pereirine and flavopereirine in pau-pereira using Raman and SERS spectroscopies

Supplementary files

Article information

Article type
Paper
Submitted
18 Mar 2019
Accepted
08 Jun 2019
First published
10 Jun 2019

New J. Chem., 2019,43, 11200-11208

Tracking pereirine and flavopereirine in pau-pereira using Raman and SERS spectroscopies

L. F. Maia, M. R. Almeida, D. F. Carvalho, N. M. P. Rosa, A. C. Sant’Ana, L. A. S. Costa, V. E. de Oliveira, A. C. Pinto and L. F. C. de Oliveira, New J. Chem., 2019, 43, 11200 DOI: 10.1039/C9NJ01314H

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