Issue 59, 2019

A FRET probe for the detection of alkylating agents

Abstract

Herein, we describe a new strategy for the detection of reactive alkylating agents such as alkyl halides. These toxic compounds react with a FRET-based profluorescent probe, triggering a self-immolative elimination at room temperature, thus leading to a fluorescence signal.

Graphical abstract: A FRET probe for the detection of alkylating agents

Supplementary files

Article information

Article type
Communication
Submitted
07 Jun 2019
Accepted
28 Jun 2019
First published
28 Jun 2019

Chem. Commun., 2019,55, 8655-8658

A FRET probe for the detection of alkylating agents

W. Tuo, J. Bouquet, F. Taran and T. Le Gall, Chem. Commun., 2019, 55, 8655 DOI: 10.1039/C9CC04391H

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