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Abstract | Cited by

Here we report a combined fluorescence and mass spectrometry assay which is capable of stably visualizing and quantifying cellular nucleoside-labeled RNA production and degradation. The fluorescence and mass spectrometry signals from cellular labeled RNAs show a linear correlation. This simple and robust assay benefits the biological community to study RNA metabolism.

Graphical abstract: Visualization and quantification of cellular RNA production and degradation using a combined fluorescence and mass spectrometry characterization assay

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