Issue 17, 2018

Total synthesis of (±)-swermirin

Abstract

The total synthesis of the anti-HBV natural product (±)-swermirin is described. Key steps include two sequential regioselective Stille cross coupling reactions, selective oxidative cleavage and spontaneous 6π-electrocyclization.

Graphical abstract: Total synthesis of (±)-swermirin

Supplementary files

Article information

Article type
Research Article
Submitted
02 Jul 2018
Accepted
25 Jul 2018
First published
27 Jul 2018

Org. Chem. Front., 2018,5, 2552-2554

Total synthesis of (±)-swermirin

P. He and Z. Wang, Org. Chem. Front., 2018, 5, 2552 DOI: 10.1039/C8QO00655E

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