Issue 17, 2018
From the journal:

Organic Chemistry Frontiers

Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones†

Jun Wei,a   Dongyan Gu,a   Shengdan Wang,a   Jinbo Hu,b   Xiaowu Dong ORCID logo a  and  Rong Sheng ORCID logo *a  

* Corresponding authors

a Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People's Republic of China
E-mail: shengr@zju.edu.cn

b Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai, People's Republic of China

Abstract

A novel class of shelf-stable and easily scalable arylthiodifluoromethyl 2-pyridyl sulfone derivatives was developed as powerful arylthiodifluoromethylation reagents, which allow efficient radical arylthiodifluoromethylation of various isocyanides to form phenanthridines and isoquinolines in good to excellent yields.

Graphical abstract: Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8QO00644J
Article type
Research Article
Submitted
30 Jun 2018
Accepted
26 Jul 2018
First published
27 Jul 2018

Org. Chem. Front., 2018,5, 2568-2572

Permissions

Request permissions

Visible-light-mediated radical arylthiodifluoromethylation of isocyanides with fluorinated 2-pyridyl sulfones

J. Wei, D. Gu, S. Wang, J. Hu, X. Dong and R. Sheng, Org. Chem. Front., 2018, 5, 2568 DOI: 10.1039/C8QO00644J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements