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Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Kunal Nepali a, Sunil Kumar a, Hsiang-Ling Huang a, Fei-Chiao Kuo a, Cheng-Hsin Lee a, Ching-Chuan Kuo b, Teng-Kuang Yeh b, Yu-Hsuan Li a, Jang-Yang Chang c, Jing-Ping Liou a and Hsueh-Yun Lee *a
aSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan. E-mail: hyl@tmu.edu.tw; Tel: +886-2-27361661 ext 6134
bInstitute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
cNational Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan

Received 30th May 2018 , Accepted 30th May 2018

First published on 15th June 2018


Abstract

Correction for ‘2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition’ by Kunal Nepali et al., Org. Biomol. Chem., 2016, 14, 716–723.


The authors regret that in Fig. 2 and Scheme 1 the R group for compound 15 was incorrectly assigned as N,N-dimethylethylamino. The correct R group is N,N-dimethylaminopropylamino as shown in the corrected structure of 15 below.


image file: c8ob90080a-u1.tif
In the discussion in the ‘In vitro cell growth inhibitory activity’ section ‘Compound 15, with a N-(N,N-dimethylaminoethyl)amino group at C6 exhibits moderate inhibitory activity towards the cancer cells tested with a mean IC50 value of 0.67 μM.’ should be corrected to ‘Compound 15, with a N,N-dimethylaminopropylamino group at C6 exhibits moderate inhibitory activity towards the cancer cells tested with a mean IC50 value of 0.67 μM.’

In addition, in the experimental details for compound 15 a singlet peak at δ 2.36 (s, 6H) was omitted.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


This journal is © The Royal Society of Chemistry 2018
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