Qi Liu, Jie-Jie Liu, Liang Cheng, Dong Wang and Li Liu
Org. Biomol. Chem., 2018,16, 5228-5231
DOI:
10.1039/C8OB01380B,
Communication
Highly selective and catalyst-free tandem multi-functionalization of terminal alkynes was developed with 2-oxindoles and benzo-furan-2(3H)-one using TEMPO both as a radical promoter and a trapping reagent. This work expands the scope of the radical-cascade addition/trapping process of alkynes for the effective construction of various β-oxyl carbonyls in moderate to good yields.
