Issue 15, 2018
From the journal:

Nanoscale

nCVTs: a hybrid smart tumour targeting platform†

Wei Jiang Goh,ab   Shui Zou,b   Bertrand Czarnyc  and  Giorgia Pastorin ORCID logo *abd  

* Corresponding authors

a NUS Graduate School for Integrative Sciences and Engineering, Centre for Life Sciences (CeLS) 28 Medical Drive, #05-01, Singapore 117456
E-mail: phapg@nus.edu.sg
Tel: +65 65161876

b Department of Pharmacy, National University of Singapore, Lower Kent Ridge Road, 18 Science Drive 2, Singapore 117543

c School of Materials Science and Engineering (MSE) & Lee Kong Chian School of medicine (LKCmedicine), Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798

d NUSNNI-NanoCore, National University of Singapore, T-Lab Level 11, 5A Engineering Drive 1, Singapore 117580

Abstract

A hybrid drug delivery platform involving the fusion of cell membranes from U937 monocytes and synthetic lipids to create nano-cell vesicle technology systems (nCVTs) is designed. nCVTs are engineered for a targeted approach towards tumour sites by preserving key surface proteins from U937 monocytes, while being amendable to functionalization and loading due to their liposomal components.

Graphical abstract: nCVTs: a hybrid smart tumour targeting platform

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Article information

DOI
https://doi.org/10.1039/C7NR08720A
Article type
Communication
Submitted
22 Nov 2017
Accepted
08 Mar 2018
First published
13 Mar 2018

Nanoscale, 2018,10, 6812-6819

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nCVTs: a hybrid smart tumour targeting platform

W. J. Goh, S. Zou, B. Czarny and G. Pastorin, Nanoscale, 2018, 10, 6812 DOI: 10.1039/C7NR08720A

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