Issue 51, 2018

Raman fingerprints of amyloid structures

Abstract

Structural differences in pathological and functional amyloid fibrils have been investigated by Raman microspectroscopy. Second-derivative analyses of amide-I and amide-III bands distinguish parallel in-register β-sheets from a β-solenoid. Further, spatially resolved Raman spectra reveal molecular heterogeneity in amyloid structures.

Graphical abstract: Raman fingerprints of amyloid structures

Supplementary files

Article information

Article type
Communication
Submitted
20 Apr 2018
Accepted
08 May 2018
First published
14 May 2018

Chem. Commun., 2018,54, 6983-6986

Raman fingerprints of amyloid structures

J. D. Flynn and J. C. Lee, Chem. Commun., 2018, 54, 6983 DOI: 10.1039/C8CC03217C

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