Dan Li, Juan Cheng, Cheng-Kun Wang, Huazhou Ying, Yongzhou Hu, Feng Han and Xin Li
Chem. Commun., 2018,54, 8170-8173
DOI:
10.1039/C8CC02830C,
Communication
By the strategy of equipping a fluorophore with two reaction triggers that are tailored to the specific chemistry of peroxynitrite, we have developed a highly selective probe for detecting peroxynitrite in live cells. Sequential response by the two triggers enabled the probe to reveal various degrees of nitrosative stress in live cells via a sensitive emission colour change.