Synthesis of indolines via a palladium/norbornene-catalyzed reaction of aziridines with aryl iodides

Abstract

A Pd- and norbornene-catalyzed domino procedure has been developed to synthesize indoline compounds. This reaction provides efficient access to indolines by employing aryl iodides with aziridines as new electrophiles. The transformation is scalable and tolerates a range of functional groups.