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Correction: Maintenance of the spheroid organization and properties of glandular progenitor cells by fabricated chitosan based biomaterials

Hao-Wei Lee a, Ya-Chuan Hsiao bc, Tai-Horng Young a and Tsung-Lin Yang *def
aInstitute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan
bDepartment of Ophthalmology, Zhongxing Branch, Taipei City Hospital, Taipei, Taiwan
cDepartment of Ophthalmology, College of Medicine, National Yang-Ming University, Taipei, Taiwan
dDepartment of Otolaryngology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan. E-mail: yangtl@ntu.edu.tw; Fax: +886-2-23940049; Tel: +886-2-23123456 ext. 63526
eResearch Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan
fGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, 10002, Taiwan

Received 15th May 2018 , Accepted 15th May 2018

First published on 1st June 2018


Abstract

Correction for ‘Maintenance of the spheroid organization and properties of glandular progenitor cells by fabricated chitosan based biomaterials’ by Hao-Wei Lee et al., Biomater. Sci., 2018, DOI: 10.1039/c7bm00559h.


The authors regret the omission of some information from Fig. 3 in the original manuscript. The corrected Fig. 3 is shown below.
image file: c8bm90022a-f3.tif
Fig. 3 Suppression of salisphere cavitation by chitosan. (a) Illustration showing the in vitro culture system for salispheres with chitosan-coated substrata. (b) Representative phase and sectioned H&E images of salispheres cultured in the control and chitosan groups. (c) Serial sections of a single salisphere to demonstrate cavitation. (d) Representative phase (upper panels) and H&E (lower panels) images of 9-day-old salispheres cultured on chitosan-coated substrata with concentrations ranging from 0.5% to 3% (w/v). (e) Incidence of cavitation at the indicated time-points of culture of control (black-filled dots) and chitosan (Chi, white-filled dots) groups. (f) Quantitative analysis of the incidence of spheroid cavitation. (g) Culture system composed of soluble chitosan. (h) Morphological phenotypes shown in the phase images (upper panels) and sectioned images (H&E, lower panels) of the salispheres cultured by coated chitosan (Chi) and soluble chitosan (ChiM). (i) Quantitation of cavitation in the 9-day-old salispheres cultured with Chi or ChiM. (j) Quantitation of cavitation in the 9-day-old salispheres cultured with control or ChiM. (k) Quantitative analysis of the incidence of spheroid cavitation with different concentrations of soluble chitosan. (l) Representative images of the phase (upper panels) and H&E staining (lower panels) of salispheres cultured with chitosan of different molecular weights. (m) Quantification of the ratios of cavitation in the groups with different molecular weight chitosan (HMW: high molecular weight and LMW: low molecular weight; scale bar = 50 μm in the phase images; b, c and d: scale bar = 100 μm in H&E images; and *p < 0.05; **p < 0.01; ***p < 0.001, t-test.).

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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