William D.
Lambert
a,
Samuel L.
Scinto
a,
Olga
Dmitrenko
a,
Samantha J.
Boyd
a,
Ronald
Magboo
b,
Ryan A.
Mehl
c,
Jason W.
Chin
*d,
Joseph M.
Fox
*a and
Stephen
Wallace
*de
aBrown Laboratory, Department of Chemistry & Biochemistry, University of Delaware, Newark, Delaware 19716, USA. E-mail: jmfox@udel.edu
bLotus Separations LLC, Newark, DE 19711, USA
cDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, USA
dMedical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK
eInstitute of Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, UK
First published on 29th August 2017
Correction for ‘Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling’ by William D. Lambert et al., Org. Biomol. Chem., 2017, 15, 6640–6644.
Very recently, Lemke, Kele and coworkers reported the genetic incorporation of dioxo-TCO 2 and demonstrated that the lower lipophilicity of this molecule resulted in improved washout times during imaging experiments. In Diels–Alder reactions with tetrazines, the reaction rate with 2 is similar to that with the parent TCO.35,40
The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.
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