Issue 45, 2017

Water-soluble and UV traceable isatoic anhydride-based reagents for bioconjugation

Abstract

Isatoic anhydride is elaborated to water soluble bioconjugation reagents that gives functionality and water solubility in one self-cleaning step. This new platform offers high atom economy with carbon dioxide being the only byproduct, and is shown to very quickly and efficiently label proteins in bicarbonate buffered solutions.

Graphical abstract: Water-soluble and UV traceable isatoic anhydride-based reagents for bioconjugation

Supplementary files

Article information

Article type
Communication
Submitted
22 Sep 2017
Accepted
04 Nov 2017
First published
06 Nov 2017

Org. Biomol. Chem., 2017,15, 9599-9602

Water-soluble and UV traceable isatoic anhydride-based reagents for bioconjugation

A. Fessler, C. Garmon, T. Heavey, A. Fowler and C. Ogle, Org. Biomol. Chem., 2017, 15, 9599 DOI: 10.1039/C7OB02377D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements