Issue 99, 2017
From the journal:

Chemical Communications

The impact of metal complex lipids on viscosity and curvature of hybrid liposomes†

Ryo Ohtani, ORCID logo *a   Tsukasa Tokita,b   Tomohisa Takaya, ORCID logo b   Koichi Iwata, ORCID logo *b   Masanao Kinoshita,c   Nobuaki Matsumori, ORCID logo c   Masaaki Nakamura,a   Leonard F. Lindoyd  and  Shinya Hayami ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan
E-mail: hayami@kumamoto-u.ac.jp, ohtani@kumamoto-u.ac.jp

b Department of Chemistry, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo 171-8588, Japan
E-mail: koichi.iwata@gakushuin.ac.jp

c Department of Chemistry, Faculty of Science, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan

d School of Chemistry, The University of Sydney, Australia

Abstract

A morphology transformation of hybrid liposomes was shown to occur from spherical vesicles to tubular micelles when increasing the ratio of the metal complex lipid present. Phase transition temperatures increased while viscosities decreased, indicating that the hybrids exhibit stronger interaction between heads but weaker interaction between alkyl chains than occurs in pristine liposomes.

Graphical abstract: The impact of metal complex lipids on viscosity and curvature of hybrid liposomes

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Article information

DOI
https://doi.org/10.1039/C7CC07944C
Article type
Communication
Submitted
14 Oct 2017
Accepted
17 Nov 2017
First published
17 Nov 2017

Chem. Commun., 2017,53, 13249-13252

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The impact of metal complex lipids on viscosity and curvature of hybrid liposomes

R. Ohtani, T. Tokita, T. Takaya, K. Iwata, M. Kinoshita, N. Matsumori, M. Nakamura, L. F. Lindoy and S. Hayami, Chem. Commun., 2017, 53, 13249 DOI: 10.1039/C7CC07944C

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