John Collins, Ting Zhang, Sung Won Oh, Robert Maloney and Jinglin Fu
Chem. Commun., 2017,53, 13059-13062
DOI:
10.1039/C7CC07361E,
Communication
We present a robust and simple method to prepare DNA-crowded enzyme complexes by directly assembling long DNA duplexes on the enzyme surface. DNA-crowded enzyme complexes show boosted substrate turnover numbers, and increased stabilities against various storage conditions. They could be potentially scaled up for applications in biomaterials and biotechnology.
