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Abstract | Cited by

A new silver-promoted [3+2] cycloaddition of azomethine ylides with isocyanides has been described. The methodology provides an efficient and modular approach to 1,2,4-trisubstituted imidazoles of vital bioactive molecules and atypical antipsychotics analogues.

Graphical abstract: Azomethine-isocyanide [3+2] cycloaddition to imidazoles promoted by silver and DBU

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