Issue 4, 2016
From the journal:

RSC Advances

A facile, one-pot procedure for the conversion of aromatic aldehydes to esters, as well as thioesters and amides, via acyl hydrazide intermediates†

Antoine Maruani,a   Maximillian T. W. Lee,a   George Watkins,a   Ahmed R. Akhbar,a   Henry Baggs,a   André Shamsabadi,a   Daniel A. Richardsa  and  Vijay Chudasama*a  

* Corresponding authors

a Department of Chemistry, University College London, 20 Gordon Street, London, UK
E-mail: v.chudasama@ucl.ac.uk

Abstract

Herein we present an efficient method for the synthesis of esters from aromatic aldehydes via readily accessible acyl hydrazides. The developed reaction protocol is shown to be tolerant of a range of aromatic aldehydes, bearing various functionalities, as well as being amenable to the synthesis of thioesters and amides.

Graphical abstract: A facile, one-pot procedure for the conversion of aromatic aldehydes to esters, as well as thioesters and amides, via acyl hydrazide intermediates

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Article information

DOI
https://doi.org/10.1039/C5RA26842G
Article type
Paper
Submitted
24 Nov 2015
Accepted
15 Dec 2015
First published
18 Dec 2015

RSC Adv., 2016,6, 3372-3376

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A facile, one-pot procedure for the conversion of aromatic aldehydes to esters, as well as thioesters and amides, via acyl hydrazide intermediates

A. Maruani, M. T. W. Lee, G. Watkins, A. R. Akhbar, H. Baggs, A. Shamsabadi, D. A. Richards and V. Chudasama, RSC Adv., 2016, 6, 3372 DOI: 10.1039/C5RA26842G

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