Jiawen Li, Guiping Qin and Hanmin Huang
Org. Biomol. Chem., 2016,14, 10572-10575
DOI:
10.1039/C6OB02136K,
Communication
A novel silver-catalyzed nucleophilic substitution of aminals with ethyl diazoacetate producing β-amino-α-diazoesters has been developed. A series of aminals with different amino moieties and substituents were successfully incorporated in this reaction, which delivered a wide range of β-amino-α-diazocarbonyl compounds in the presence of a lower catalyst loading in 2 hours.
