A method for the palladium-catalyzed arylation of α,β-unsaturated valerolactams is reported. This new protocol provides arylation products in yields up to 95% and is applicable to a wide array of aryl and heteroaryl bromides. The optimization, scope and limitations are described.
D. P. Canterbury, K. D. Hesp and J. Polivkova, Org. Biomol. Chem., 2016, 14, 7731 DOI: 10.1039/C6OB01126H
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