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We describe and employ a high-throughput screening method to accelerate the synthesis and identification of pure-phase, nanocrystalline metal–organic frameworks (MOFs). We demonstrate the efficacy of this method through its application to a series of porphyrinic zirconium MOFs, resulting in the isolation of MOF-525, MOF-545, and PCN-223 on the nanoscale.

Graphical abstract: High-throughput synthesis and characterization of nanocrystalline porphyrinic zirconium metal–organic frameworks

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