Issue 35, 2016
From the journal:

Chemical Communications

A near-infrared AIEgen for specific imaging of lipid droplets†

Miaomiao Kang,‡ab   Xinggui Gu,‡ac   Ryan T. K. Kwok,ac   Chris W. T. Leung,ac   Jacky W. Y. Lam,ac   Feng Li*bd  and  Ben Zhong Tang*ace  

* Corresponding authors

a Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration & Reconstruction, Institute for Advanced Study, Division of Biomedical Engineering, Division of Life Science, State Key Laboratory of Molecular Neuroscience and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China
E-mail: tangbenz@ust.hk

b Department of Neurobiology and Anatomy, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
E-mail: lifeng@mail.sysu.edu.cn

c HKUST Shenzhen Research Institute, No. 9 Yuexing 1stRD, South Area, Hi-tech Park, Nanshan, Shenzhen 518057, China

d Guangdong Provincial Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China

e Guangdong Innovative Research Team, SCUT-HKUST Joint Research Laboratory, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, China

Abstract

A new near-infrared AIE luminogen (TPE-AC) with high specificity, good biocompatibility and excellent photostability is designed and synthesized for lipid droplet (LD) imaging in cells. TPE-AC can monitor the process of LD accumulation in cells, thus making it potential for the diagnosis of early-stage fat-related diseases.

Graphical abstract: A near-infrared AIEgen for specific imaging of lipid droplets

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Article information

DOI
https://doi.org/10.1039/C6CC01797E
Article type
Communication
Submitted
29 Feb 2016
Accepted
29 Mar 2016
First published
29 Mar 2016

Chem. Commun., 2016,52, 5957-5960

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A near-infrared AIEgen for specific imaging of lipid droplets

M. Kang, X. Gu, R. T. K. Kwok, C. W. T. Leung, J. W. Y. Lam, F. Li and B. Z. Tang, Chem. Commun., 2016, 52, 5957 DOI: 10.1039/C6CC01797E

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