Issue 4, 2016

A simple excited-state intramolecular proton transfer probe based on a new strategy of thiol–azide reaction for the selective sensing of cysteine and glutathione

Abstract

A simple azido-substituted fluorescent sensor AHBO showing a selective turn-on response to cysteine (Cys) and glutathione (GSH) over homocysteine (Hcy), sulfide and other amino acids has been constructed, which is based on the mechanism of selective nucleophilic substitution–rearrangement reactions.

Graphical abstract: A simple excited-state intramolecular proton transfer probe based on a new strategy of thiol–azide reaction for the selective sensing of cysteine and glutathione

Supplementary files

Article information

Article type
Communication
Submitted
31 Aug 2015
Accepted
02 Nov 2015
First published
02 Nov 2015

Chem. Commun., 2016,52, 749-752

A simple excited-state intramolecular proton transfer probe based on a new strategy of thiol–azide reaction for the selective sensing of cysteine and glutathione

D. Zhang, Z. Yang, H. Li, Z. Pei, S. Sun and Y. Xu, Chem. Commun., 2016, 52, 749 DOI: 10.1039/C5CC07298K

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