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Correction: Tailor-made gemcitabine prodrug nanoparticles from well-defined drug–polymer amphiphiles prepared by controlled living radical polymerization for cancer chemotherapy

Weiwei Wang a, Chen Li a, Ju Zhang a, Anjie Dong b and Deling Kong *a
aTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, 300192, China. E-mail: kongdeling@nankai.edu.cn
bSchool of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China

Received 5th February 2015 , Accepted 5th February 2015

First published on 10th February 2015


Abstract

Correction for ‘Tailor-made gemcitabine prodrug nanoparticles from well-defined drug–polymer amphiphiles prepared by controlled living radical polymerization for cancer chemotherapy’ by Weiwei Wang et al., J. Mater. Chem. B, 2014, 2, 1891–1901.


The authors would like to acknowledge and apologise for using some text from references 1 and 2 (below) without appropriate attribution in some sentences from sections 3.1 and 3.6 and that Scheme 1 was redrawn from Scheme 1 in reference 2 without appropriate attribution. The authors would like to clarify that this work is not the first example of such an amphiphilic polymer and related work is cited in the manuscript.

The in vivo drug concentration dose is incorrectly stated as 26 mg kg−1 throughout the manuscript (Abstract, sentence 8; section 2.8, paragraph 2, sentence 5; section 3.6, sentence 2; Discussion, paragraph 7, sentence 9). The correct dose administered was 0.693 mg mL−1 obtained by concentrating the nanoparticle suspensions and the injection volume was 250 μL.

In several instances (section 3.1, paragraph 2, sentence 8; section 3.2, sentence 5; Table 1, column 7) the drug loading should be 30.4% and 17.7% for PMMA5 and PMMA11.2, rather than 43.7% and 21.5%, respectively. The drug loading in the manuscript had been calculated using the formula Gem/PMMA, rather than by the more accurate formula Gem/(Gem + PMMA).

The conclusions remain unchanged.

 

References

1 D. Trung Bui, A. Maksimenko, D. Desmaële, S. Harrisson, C. Vauthier, P. Couvreur and J. Nicolas, Biomacromolecules, 2013, 14, 2837–2847.

2 S. Harrisson, J. Nicolas, A. Maksimenko, D. T. Bui, J. Mougin and P. Couvreur, Angew. Chem., Int. Ed., 2013, 52, 1678–1682.

 

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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